Two people died from injuries suffered in a crash about 5 p.m. Friday on Illinois 152 just west of Sacred Heart Road in Perry County, Illinois State Police said.
Preliminary investigation indicates one passenger vehicle was westbound on Illinois 152. The other passenger vehicle was eastbound.
It appears the driver of the westbound vehicle lost control, entering the eastbound lane and into the path of the eastbound vehicle.
The drivers of both units were air evacuated with serious injuries. Both passengers in the westbound vehicle suffered fatal injuries.
Both passengers in the second vehicle were taken to Pinckneyville Community Hospital, where they were treated and released.
Further information was unavailable Friday night. The investigation continues.